As long as you are running the same protocols on the NT4 machine and the OS/2 Warp machines, it should all work together. There is an IBM redbook which looks at network interoperability at:http://publib-b.boulder.ibm.com/Redbooks.nsf/RedbookAbstracts/sg244786.html
It may offer some help.
There is also a FAQ which might help at:
http://home.austin.rr.com/byteenable/sea.htm
Hope this helps.